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Akkermat
Akkermat 150mg
Redução do apetite ao promover sensação de saciedade por múltiplos mecanismos, • Regulação do metabolismo lipídico com aumento da taxa metabólica
De R$ 205,00
por R$193,35
Benefícios
• Redução do apetite
• Melhora da compulsão alimentar
• Gerenciamento de peso
• Anti-inflamatório natural
• Pacientes resistentes as terapias convencionais com GLP-1 sintéticos
• Desmame após o uso de análogos de GLP-1
Formulação
Akkermat 150mg
Posologia
Via oral, na dose 150 mg ao dia, após a refeição
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Descrição
Aplicações
• Redução do apetite ao promover sensação de saciedade por múltiplos mecanismos
• Regulação do metabolismo lipídico com aumento da taxa metabólica (termogênico)
• Aumento da temperatura corpórea
• Aumento do consumo de oxigênio
• Melhora do perfil lipídico
• Redução de marcadores inflamatórios
Referências
- Material do fornecedor, 2023.
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- Joseph, A., Johannah, N. M., Kumar, S., Maliakel, B., & Krishnakumar, I. M. (2020). Safety assessment of a fenugreek dietary fiber-based formulation of capsaicinoids-rich red chili extract (Capsifen®): Acute and sub-chronic studies. Toxicology Reports, 7, 602-609.
- Joseph, A., Balakrishnan, A. M., Mulakal, J. N., Sivadasan, S. D., Mohan, R., Maliakel, B., & Madhavamenon, K. I. (2021a). A green approach for the sustained-intestinal delivery of red chili (Capsicum annum L) extracted capsaicinoids with enhanced bioavailability. Journal of Functional Foods, 85, 104658.
- Joseph, MSc, A., John, PhD, F., Thomas, MSc, J. V., Sivadasan, S. D. P., Maliakel, PhD, B., Mohan, PhD, R., & IM, K. (2021b). Influence of a novel food-grade formulation of red chili extract on overweight subjects: randomized, double-blinded, placebo-controlled study. Journal of Dietary Supplements, 18(4), 387-405.
- Joseph, A., Shanmughan, P., Balakrishnan, A., & Maliakel, B. (2022). Enhanced Bioavailability and Pharmacokinetics of a Natural Self-Emulsifying Reversible Hybrid-Hydrogel System of Quercetin: A Randomized Double-Blinded Comparative Crossover Study. ACS omega.
- Roopashree, N., Syam, D. S., Krishnakumar, I. M., Mala, K. N., Fleenor, B. S., & Thomas, J. (2024). A natural sustainedintestinal release formulation of red chili pepper extracted capsaicinoids (Capsifen®) safely modulates energy balance and endurance performance: a randomized, double-blind, placebo-controlled study. Frontiers in Nutrition, 11, 1348328.
- Ludy, M. J., & Mattes, R. D. (2011). The effects of hedonically acceptable red pepper doses on thermogenesis and appetite. Physiology & Behavior, 102(3-4), 251-258.
- Ludy, M. J., Moore, G. E., & Mattes, R. D. (2012). The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans. Chemical senses, 37(2), 103-121.
- Luo, X. J., Peng, J., & Li, Y. J. (2011). Recent advances in the study on capsaicinoids and capsinoids. European Journal of Pharmacology, 650(1), 1-7.
- Sanati, S., Razavi, B. M., & Hosseinzadeh, H. (2018). A review of the effects of Capsicum annuum L. and its constituent, capsaicin, in metabolic syndrome. Iranian Journal of Basic Medical Sciences, 21(5), 439.
- Shen, W., Shen, M., Zhao, X., Zhu, H., Yang, Y., Lu, S., ... & Le, S. (2017). Anti-obesity effect of capsaicin in mice fed with high-fat diet is associated with an increase in population of the gut bacterium Akkermansia muciniphila. Frontiers in Microbiology, 8, 272.
- Si, J., Kang, H., You, H. J., Ko, G. (2022). Revisiting the role of Akkermansia muciniphila as a therapeutic bacterium. Gut Microbes, 14(1), 2078619.
- Smeets, A. J., & Westerterp-Plantenga, M. S. (2009). The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. European journal of nutrition, 48, 229-234.
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- Yue, C., Chu, C., Zhao, J., Zhang, H., Chen, W., & Zhai, Q. (2022). Dietary strategies to promote the abundance of intestinal Akkermansia muciniphila, a focus on the effect of plant extracts. Journal of Functional Foods, 93, 105093.
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Recomendações
Não deve ser utilizado em crianças, gestantes, lactantes e pacientes que apresentam doenças intestinais, úlcera gástrica, cistite crônica e de repetição, hemorroida e alérgicos a pimenta.






